The tumor microenvironment (TME) is an important mediator 150 of breast cancer progression.Cancer-associated fibroblasts constitute a major component of the TME and may originate from tissue-associated fibroblasts or infiltrating mesenchymal stromal cells (MSCs).The mechanisms by which cancer cells activate fibroblasts and recruit MSCs to the TME a
Abstract Background Infectious diseases, such as the latest COVID pandemic, caused by microorganisms like bacteria and virus, wreak havoc shaking human civilization with its rapid infection rate, and high number of mortalities.In case of a contagious disease, the virus can survive on any surface over a period of time and can be transferred to the h
Abstract In 2019 and 2020, we investigated the individual and combined effects of two biofertilizers (manure tea and bioinoculant) and one humic acid (HA) product on cannabis biochemical and physiological parameters TEA TOWEL and soil CO2 evolution under outdoor conditions.Our hypothesis was that HA would increase the microbial activity in the biof
The accounting expert profession should be a noble one.It should be respected by third parties as well as the accounting professional in question.The work of a professional accountant involves, among other responsibilities, the elaboration of judicial accounting expertise reports.Unfortunately, the content of certain reports 150 filed in court is n
Abstract Fungi are very common infectious pathogens, which may cause invasive and potentially life-threatening infections.However, the efficacy of antifungal medications remains limited.Herein, Bed Canopy a Cu2+-phenolic nanoflower is designed to combat fungal infections by combining cuproptosis and cell wall digestion.Firstly, protocatechuic acid